1. SOLVED: Keyboard and mouse stopped working in Adobe Flash (64-bit)
Bug https://bugs.launchpad.net/ubuntu/+source/flashplugin-nonfree/+bug/410407 has been updated with a solution that worked for me (there are other alternatives as well, not as nice):
"gksudo gedit /usr/lib/
Then add: export GDK_NATIVE_
This is once again good lesson from what happens when proprietary binaries are included in open source systems.
2. SOLVED: USB mouse & keyboard randomly don't work after standby
Not yet confirmed, do the same as for 8.10: http://fonsen.blogspot.com/2009/03/ubuntu-fixing-lost-usb-keyboardmouse-in.html
It seems that update-manager wisely commented out previous fix by stating that HAL is now used.
3. SOLVED: Apport reporting serious errors when waking up from standby
A recommended software update in November seems to have taken care of the issue.
4. SOLVED: Spotify sound stopped working
Solution upgrade to wine 1.2 using aptitude:
There's still some problems with album browsing but that did work before and stopped working before upgrade. Playing and searching work.